Spectrometry Instrumentation and Techniques

General questions about mass measurement and mass spectrometry 96 

Separation techniques gas chromatography (GC), and high-performance liquid 

Fast-atom bombardment (FAB) and liquid secondary ion mass 

Matrix-assisted laser desorption/ionization (MALDI) 116 

Interactions with a magnetic field magnetic (B) analyzer 124 

---

Roboz, J., Introduction to Mass Spectrometry, Instrumentation and Techniques. Wiley (Interscience), New York, 1968. 

Mason, E. A. and McDaniel, E. W. Originally published in 1988 by Wiley. Introduction to Mass Spectrometry Instrumentation and Techniques. 

Dr. Roboz has more than 135 publications. His first book, Introduction to Mass Spectrometry Instrumentation and Techniques (Wiley, 1968), was reprinted in 2000 by the American Society for Mass Spectrometry in the Classic Works in Mass Spectrometry series. His second book, in 2002, Mass Spectrometry in Cancer Research (CRC Press), won a commendation award from the British Medical Association. 

In this chapter we provide a general overview of mass spectrometry instrumentation and techniques. After the discussion of some general questions and main features of mass spectrometers, the ionization methods, separation techniques, mass analyzers, and tandem mass spectrometry will be discussed. At the end of the chapter, a few arbitrarily chosen mass spectrometry terms will be mentioned for clarification. Somewhat surprisingly, these terms are not well understood and misleadingly used in everyday jargon. 

---