Spatial Imaging detector system

A notable multichannel spectrometer which does not use an IPDA is the SIDS (Spatial Imaging Detector System) spectrometer... 

One can use a low spatial resolution detector system, because the naltrexone blocks all p opiate receptors in the brain regardless of their location, and they are widespread throughout the brain. Probe devices for use with positron-emitting tracers have been used frequently to study mice, rats, dogs, baboons, and humans. In living mice, it was possible to obtain a dose-response curve for haloperidol on the binding of [ C]M-methyl spiperone. Similar dose/response curves were obtained in humans, and the results correlated well with PET imaging studies of the same persons. 

The germanium detector array allows us to take maximum advantage of a focused gamma-ray beam to spatially resolve the source. The focal spot can be easily localized looking at the 9 count rates. This also allows imaging of an off-axis source. Fig. 1 shows a series of measurements in which the source-lens-detector system has been intentionally misaligned. 

The performance of an imaging system for IFM depends on several parameters including the temporal, spatial, and spectral resolution, the imaging detector sensitivity (signal-to-noise ratio), and the image analysis hard and software used to quantify and document the results. 

PI AS is an acronym for Photocounting Image Aquisation System. Its basic principle is illustrated in Fig. 4.123. The photons from a light source fall onto the photocathode of an image intensifier where they release electrons which are amplified in a multichannel canal plate (MCP) and are imaged onto a position sensitive detector. A computer software analyses the data and gives the measured spectrum or the spatial variation of the intensity from extended sources [284, 285]. 

Both TCSPC and TG benefit from operation in SPC mode. SPC results in little or no noise and a high photon-economy [10]. Therefore, TCSPC and TG are ideal for high spatial and lifetime resolution imaging [24], Both techniques offer high image contrast also on dim samples. However, the dead-time of the detectors and the point scanning character limit the throughput of these systems. 

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