Solution-phase synthesis drying

Kim et al. have developed a solution-phase synthesis method of ultralarge GO sheets involving pre-exfoliation of graphite flakes. Such large GO sheets spontaneously form lyotropic nematic phase at a very low concentration in water [125]. They produced self-assembled brick-Uke GO nanostmctures by simple casting of GO dispersions and drying in ambient conditions. These free-standing GO papers... 

Synthesis of 3-Acetylthio-2-alkyl Alkanals. Piperidine (100 pL) was added to alkenals 5a-f (34 mmol) under nitrogen at 10 °C in separated cylinders of die Quest 205 apparatus. Thioacetic acid (3.68 mL, S1.6 mmol) was dien added d op-wise at 10 °C. Thereafter, the reaction mixture was stirred for another 18 h at room temperature. The mixture was diluted widi Et20 (10 mL), washed first with HCl (10 mL, 1 N) and then twice with a saturated NaHCOa solution (10 mL). The organic phases were dried over Na2S04. All these steps were carried out at the same time in the Quest 205. Then, the solvent was evaporated for each sample. The GC purity of the crude products was 50-90%, depending on the starting alkenal. In each case, a mixture of the two diastereomers was obtained. The detailed analytical description of the 3-acelylthio-2-alky-alkanals 6a-f has been reported elsewhere (//). 

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