Solubility on Sample Purity

During scale-up of a multistep chemical synthesis the chemical purity of samples is often very variable. This is a major issue for process optimization of 

In production-scale processes, the purity of the samples also depends on the quality of the raw material (e.g., educts for chemical reactions) as well as on the equipment used. To avoid problems in the subsequent separation process the influence of purity on solubility must be checked after the first amounts of the actual sample are available. 

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