Solubility analysis using pressure filtration

In systems where the liquid phase interaction between the solute and solvent is close to ideal, then Eq. 2 can be used successfully on it s own to fit and extrapolate solubility data with respect to temperature. The technique is valuable in an industrial setting, where time pressures are always present. Solubility data points are often available without any additional effort, from initial work on the process chemistiy. The relative volume of solvent that is required to dissolve a solute at the highest process temperature in the ciystallization is often known, together with the low temperature solubility by analysis of the filtrates. If these data points fit reasonably well to the ideal solubility equation then it can be used to extrapolate the data and predict the available crystallization yield and productivity. This quickly identifies if the process will be acceptable for long term manufacture, and if further solvent selection is necessary. 

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