Solid phase synthesis of protected peptide fragments

Wang SS. p-Alkoxybenzyl alcohol resin and p-alkoxybenzyloxycarbonylhy-drazide resin for solid-phase synthesis of protected peptide fragments. J Am Chem Soc 1973 95 1328-1333. 

Rink H. Solid-phase synthesis of protected peptide fragments using a trialkoxy diphenyl methylester resin. Tetrahedron Lett 1987 28 3787-3790. 

Rink, H. Solid-Phase Synthesis of Protected Peptide Fragments Using a Trialkoxydiphenyl-Methylester Resin, Tetrahedron Lett. 1987, 28, 3787-3790. 

Wang, S.-S. p-Alkoxybenzyl Alcohol Resin and p-Alkoxybenzyloxycar-bonylhydrazide Resin for Solid Phase Synthesis of Protected Peptide Fragments, J. Am. Chem. Soc. 1973, 95, 1328-1333. 

Dialkoxy- and trialkoxybenzyl esters are even more acid-labile than the Wang linker, and can, for example, be cleaved with dilute TFA, acetic acid, or hexafluoroiso-propanol without simultaneous acidolysis of Boc groups. These linkers thus enable the solid-phase synthesis of protected peptide fragments or other acid-sensitive products [33]. 

Solid phase synthesis of protected peptide fragments... 

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