Solid-phase synthesis donor-bound approach

SCHEME 54. Major concepts for the polymer-supported/solid-phase oligosaccharide synthesis glycosyl acceptor bound approach (A) and glycosyl donor bound approach (B). 

The preceding sections discussed the strengths and weaknesses of the donor- and acceptor-bound synthetic strategies developed to date for the synthesis of complex oligosaccharides. Boons et al. recently described an approach that combines both strategies in a bidirectional solid phase oligosaccharide synthesis [67]. 

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