Solid-phase extractions with fluorous silica gel

2 Solid-phase extractions with fluorous silica gel 

Fluorous solid-phase extractions are readily conducted in parallel (or serial), with or without automation. All reaction mixtures are processed identically and behave in substantially the same way, even though all the products are different. Careful fractionation and analysis are not required there is one organic fraction and one fluorous fraction. Because the separation is so easy, loading levels can be high. Loose fluorous silica gel and cartridges suitable for solid-phase extraction have recently been commercialized under the trademark FluoroF/dj/i by Fluorous Technologies, Inc.  

It is also possible to perform flash chromatographic and HPLC separations with fluorous silica gel. The HPLC separations are the cornerstone of the new technique of 

---