Solid-phase extraction using ion exchange resins

Solid-phase extraction using ion exchange resins 

Several groups reported the use of ion exchange resins for the parallel purification of small-molecular-weight compound libraries. Reaction conditions for the synthesis of the library are chosen such that the product of interest has distinctly different physical properties than the byproducts or the excess reagents. 

Similarly, excess amines could be extracted with acidic ion exchange resins as exemplified by the same group in the synthesis of ureas starting from isocyanates and amines.  

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