Solid oral dosage form Immediate release tablets

For the pharmaceutical product development scientist, there is clearly a need for objective information about the practical performance of different excipients and their various grades. In this chapter we set out to bring together the results of some of our ongoing evaluations of the physical and mechanical properties of excipients commonly used for the manufacture of solid oral dosage forms. In this particular article, we have chosen to focus on the fillers that are most commonly used in the manufacture of immediate release tablets microcrystalline cellulose (MCC), lactose, calcium phosphate, and mannitol (1). 

I Advantages. Carbamazepine was approved as an AED in 1974 and has been well studied. Oral immediate- and extended-release solid and liquid dosage forms are available. The oral solid dosage form is available as an immediate-release tablet and as a sustained-release capsule and a controlled-release tablet. The sustained- and controlled-release dosage forms allow for twice-daily dosing to reduce the... 

That tablets can be formulated to uniquely meet these criteria accounts for their emergence as the most prevalent oral solid dosage form. Although several different types of tablets may be distinguished, they are mostly made by compression, intended to be swallowed whole and designed for immediate release. This paper presents a systematic approach to the design and formulation of immediate-release compressed tablets. 

Same pharmaceutical form. Oral solid pharmaceutical forms of immediate release, such as tablets and capsules, are regarded as the same dosage form. 

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