Solid oral dosage form Hard gelatin capsules

Capsules are solid oral dosage forms in which the drug is enclosed within a hard or soft shell. The shell is normally made from gelatin and results in a simple, easy-to-swallow formulation with no requirement for a further coating step. They can be... 

The dry adsorbed emulsions have been formulated to be introduced into solid oral dosage forms such as tablets and hard gelatin capsules. The aim is to obtain a sustained release form of an active ingredient effective in small doses and characterized by a short half-time. 

In the last 15 to 20 years, there has been a huge resource in both academia and industry devoted to the development of drug delivery systems that target drugs more effectively to their therapeutic site. Much of this work has been successful and is reported within this text. In spite of this, oral solid dosage forms such as tablets and hard gelatin capsules, which have been in existence since the nineteenth century, remain the most frequently used dosage forms. This is not simply a reflection of the continued use of established products on the market, tablets and capsules still account for about half of all new medicines licensed (Table 11.1). 

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