Soft tissue augmentation material

Piacquadio D, Jarcho M, Goltz R. Evaluation of hylan b gel as a soft-tissue augmentation implant material. J Am Acad Dermatol 1997 36 544-549. 

Organopolysiloxanes (silicones) are very important materials for therapeutic applications because of their good physicochemical properties and their inertness to biochemical processes. For example, silicones are employed as ointments (especially for burns), prosthetic materials (e.g. replacement of blood vessels), and plastic surgery (e.g. augmentation of soft tissue or loose skin). 

The primary animal species from which implants for human clinical use are fashioned include bovine, equine and swine. Bovine-derived medical implants have been in clinical use for over 20 years. The majority of these are coUagen-based implants derived from Type-1 dermal collagen (Patino et al., 2002 Ramshaw et al., 2001). Other bovine tissues collected for human use include the pericardium (Li et al., 2011) as well as vascular grafts (Guidoin et al., 1989). Porcine-derived implants materials are also used in a wide array of specialities. Primary uses include porcine dermis for repair and augmentation of soft-tissue repair (Smart et al., 2014), cardiac valves (Manji et al., 2012) and small intestine (Parmenter, 2001 KnoU, 2001). To a much... 

Collagen implant material and methods for augmenting soft tissue 4,424,208 1984 Wallace and Wade... 

Biopolymers are often used throughout the human body they are also called biomedical polymers. A biomedical material can be of natural origin (biopolymer) or a synthetic polymer and can be used for any period of time, as a whole or as part of a system that treats, augments, or replaces any organ or function of the body, as well as for medical technical applications outside the body. When a prosthetic device is placed into the body, two aspects must be taken into account functional performance and biocompatibility. The former requires special functions of the biomedical polymers, in particular including load transmission and stress distribution. Biocompatibility between a polymer and a biological system (e.g., soft tissue,... 

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