Sodium oxybate Opioids

SODIUM OXYBATE 1. ALCOHOL 2. ANALGESICS - opioids 3. ANTIDEPRESSANTS-TCAs 4. ANTIEPILEPTICS-barbiturates 5. ANTIHISTAMINES 6. ANTIPSYCHOTICS 7. ANXIOLYTICS AND HYPNOTICS-BZDs, buspirone Risk of CNS depression - coma, respiratory depression Additive depression of CNS Avoid co-administration. Caution even with relatively non-sedating antihistamines (cetrizine, desloratidine, fexofenadine, levocetirizine, loratidine, mizolastine) as they can impair the performance of skilled tasks... [Pg.273]

OPIOIDS ANXIOLYTICS AND HYPNOTICS-SODIUM OXYBATE Risk of CNS depression - coma, respiratory depression Additive effect Avoid co-administration... [Pg.477]

Opioids. The UK manufacturer specifically contraindicates the use of sodium oxybate in patients taking opioids. ... [Pg.1279]

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