Sodium chloride nasal drops

Charge 50% item 1 in a suitable stainless steel container and heat to 85° to 90°C. 

---

Table 8.5 Sodium Chloride Nasal Drops, Viscous Solution 0.9 % [40]...

Nose drops and sprays that are not iso-osmotic have a negative influence on the ciliary epithelium. Hypo-osmotic solutions however are more ciliotoxic than hyper-osmotic ones [32]. Again the requirements should be more strict than for eye drops, because the diluting effect of the nasal liquid is much smaller than that of tears. Nasal drops are made iso-osmotic with sodium chloride, or in case of incompatibilities with glucose or mannitol. More information about osmotic pressure and tonicity, and the calculatimi of the osmotic value of solutions, is given in Sect. 18.5. 

Also solutions are sometimes made viscous to prevent them from flowing out of the nose, for example nasal drops with 0.9 % or 1.5 % sodium chloride (Table 8.5), but there are doubts whether this will help. 

---