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Sodium aurothiopropanol sulfonate

Severe overdosage of sodium aurothiopropanol sulfonate (1.1 g daily for 13 days) caused jaundice and skin eruptions. Liver biopsies showed modest centrilobular necrosis and significant bile stasis. Serum hepatic enzyme activities were increased. The patient was treated with dimercaprol and recovered after 2 months, although alkaline phosphatase and gamma-glutamyl-transferase activities remained high for 6 months. [Pg.1527]

FIGU RE 10.1 Chemical structures of gold thiolates used in the treatment of rheumatoid arthritis (a) aurothioglucose, (b) sodium aurothiosulfate, (c) sodium aurothiomalate, and (d) sodium aurothiopropanol sulfonate. [Pg.218]

See other pages where Sodium aurothiopropanol sulfonate is mentioned: [Pg.253]    [Pg.341]    [Pg.218]    [Pg.253]    [Pg.341]    [Pg.218]   
See also in sourсe #XX -- [ Pg.218 ]



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