Smart drug delivery device

Wienforth F, Landrock A, Schindler C, Siegert J and Kirch W (2007), Smart textiles A new drug dehvery system for symptomatic treatment of a common cold , / CZm Pharmacol, 47(5), 653-658. DOI 10.1177/0091270007299927. Bomeman AF (2002), A comparison of poly(L-lactic acid) and poly(D,L-lac-tide co-glycohde) biodegradable fibers as drug delivery devices , MS thesis,The University of Texas, Arhngton. 

Yuzhakov et al. [93] describe the production of an intracutaneous microneedle array and provide an account of its use (microfabrication technology). Various embodiments of this invention can include a microneedle array as part of a closed loop system smart patch to control drug delivery based on feedback information from analysis of body fluids. Dual purpose hollow microneedle systems for transdermal delivery and extraction which can be coupled with electrotransport methods are also described by Trautman et al. [91] and Allen et al. [100]. These mechanical microdevices which interface with electronics in order to achieve a programmed or controlled drug release are referred to as microelectromechanical systems (MEMS) devices. 

---