Small Biomolecule Detection

Spherical and Anisotropic Silver Nanomateriak in Medical Diagnosis 

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Small molecules such as dopamine,ascorbic acid, amino acids, nucleotides, NADH, and glucose have been successfully detected with QD-based biosensors. FRET-based fluorescence microscopy and electrochemistry are the most commonly used methods for small biomolecule detection using QD-based biosensors. ... 

Conventional evanescent sensing works exceedingly well for relatively small biomolecules such as proteins and DNA molecules whose size is much smaller than the decay length. However, it becomes less sensitive when detecting biospecies, such as cells, with dimensions over 1 pm. In Chap. 15, deep-probe waveguide sensors are developed to overcome this limitation, which have a decay length comparable to the size of the biospecies of interest. 

The Detection of Small Biomolecules Dairy Products in the Archaeological Record... 

Tuzimski, T. 2011, Application of different modes of thin-layer chromatography and mass spectrometry for the separation and detection of large and small biomolecules,... 

Binding assays for small molecules detection 3 Effective optical thickness (EOT) 3-4 Moderate-size biomolecules, detection and recognition 4 Organophosphorus compounds (OPCs) 4 Photoluminescence-based transducers 2 PSi nanostructures-sensing concept 3-4 Reflectance-based transducers 2 Sensing of complex samples 5... 

In the field of responsive agents, enzyme targeting has specific advantages. A small concentration of the enzyme can convert a relatively high amount of the probe in multiple catalytic cycles which considerably decreases the detection limit for the enzyme as compared to other biomolecules. Moreover, enzymatic reactions are usually highly specific therefore, the observed change... 

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