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Skeletal muscle relaxant chlorzoxazone

There are several chemically unrelated skeletal muscle relaxants. Chlorzoxazone is an example of a drug that evolved from a discovery that certain benzimidazoles had mephen-esinlike activity. Chlorzaxazone, the benzoxazole isostere, appears to have the same spectrum of activity and mechanism(s) as the polyol carbamates. [Pg.577]

Anticonvulsants Mephenytoin (Wang et al. 2004b) Skeletal muscle relaxants Chlorzoxazone (Gurley et al. 2002,2005)... [Pg.456]

The mode of action of many skeletal muscle relaxants, for example carisoprodol (Soma), baclofen (Lioresal), and chlorzoxazone (Paraflex), is not clearly understood. Many of tiiese dragp do not directly relax skeletal muscles, but dieir ability to relieve acute painful musculoskeletal conditions may be due to their sedative action. Cyclobenzaprine (Flexeril) appears to have an effect on muscle tone, tiius reducing muscle spasm. [Pg.191]

Skeletal Muscle Relaxant Combinations Carisoprodol Compound—carisoprodol, aspirin Mexaphen—chlorzoxazone, acetaminophen Lobac—salicylamide, phenyltoloxamine, acetaminophen Norgesic Fbrte—orphenadrine citrate, aspirin, caffeine Norgesic—orphenadrine citrate, aspirin, caffeine Robaxisal—methocarbamol, aspirin Sodol Compound—carisoprodol, aspirin Soma Compound—carisoprodol, aspirin... [Pg.683]

Geriatric Considerations - Summary Chlorzoxazone is a centrally acting skeletal muscle relaxant that at higher doses can cause CNS depression. It appears to have modest clinical benefits and is most often used for acute muscle discomfort as compared to chronic muscle pain. It is often taken in combination with acetaminophen. Transient CNS depressant effects place the older adult at risk for falls and related accidents when taking this drug. [Pg.258]

There is a very great demand for drugs for the relief of anxiety. This was formerly met by the use of alcohol, bromides or barbiturates, which carried the risk of abuse or dangerous toxicity. The first of the modern minor tranquilizers, introduced from 1946 onwards, were drugs described as skeletal muscle relaxants. These were mainly derivatives of polyhydric alcohols, but heterocyclic examples included metaxolone (161), which is related to the aryl ethers of glycerol, chlorzoxazone (162) and chlormezanone (163). Dantrolene sodium (164) is a muscle relaxant and CNS depressant. [Pg.169]

Chlorzoxazone (Paraflex, Parafon Forte DSC, Others) [Skeletal Muscle Relaxant/ANS Drug] Uses Adjunct to rest physical therapy to relieve discomfort associated w/ acute, painful musculoskeletal conditions Action Centrally acting skeletal muscle relaxant Dose Adults. 250-500 mg PO tid-qid Peds. 20 mg/kg/d in 3-4 + doses Caution [C, ] Avoid EtOH CNS depressants Contra Severe liver Dz Disp Tabs SE Drowsiness, tach, dizziness, hepatotox, angioedema Interactions T Effects W/ antihistamines, CNS depressants, MAOIs, TCAs, opiates, EtOH, watercress EMS Use of CNS depressants and concurrent EtOH use can T sedation urine may turn reddish purple or orange OD May cause N/V/D, dizziness, HA, X deep tendon reflexes, hypotension and resp depression symptomatic and supportive, activated charcoal may be effective... [Pg.110]

Chlorzoxazone is used as a centrally acting skeletal muscle relaxant and as an analgesic. It is also a strong oxidizing agent. [Pg.585]

Chlorzoxazone, a benzoxazole derivative with skeletal muscle relaxant properties (250 to 750 mg p.o. t.i.d.), is used as an adjunct medication in the treatment of acute and painful musculoskeletal conditions. [Pg.152]

The client with low back pain syndrome is prescribed chlorzoxazone (Parafon Forte), a skeletal muscle relaxant. Which statement by the client would warrant intervention by the nurse ... [Pg.218]


See other pages where Skeletal muscle relaxant chlorzoxazone is mentioned: [Pg.504]    [Pg.217]    [Pg.3013]    [Pg.504]    [Pg.217]    [Pg.3013]    [Pg.110]    [Pg.614]    [Pg.74]    [Pg.110]    [Pg.165]   
See also in sourсe #XX -- [ Pg.3013 ]




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Chlorzoxazone

Muscle relaxant

Muscle relaxants chlorzoxazone

Muscle relaxation

Muscle-relaxing

Skeletal muscle

Skeletal muscle relaxant

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