Single photon emission computed tomography SPECT ligands

Single photon computed emission tomography (SPECT) with the highly selective DA transporter ligand [i l] altropane was used to compare 6 adults with ADHD with a database of 30 healthy controls (Dougherty et al., 1999). Striatal binding potential (Bi ,3,j / K ) was elevated in all six ADHD patients. However, this report was questioned because 4 of the 6 patients had been previously treated with stimulants, even though they were all medication-free for at least 1 month. 

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