Single-operator characteristics

Single-operator characteristics are determined by analyzing a sample whose concentration of analyte is known to the analyst. The second step in verifying a method is the blind analysis of standard samples where the analyte s concentration remains unknown to the analyst. The standard sample is analyzed several times, and the average concentration of the analyte is determined. This value should be within three, and preferably two standard deviations (as determined from the single-operator characteristics) of the analyte s known concentration. 

Are the single-operator characteristics for this method acceptable ... 

The use of several QA/QC methods is described in this article, including control charts for monitoring the concentration of solutions of thiosulfate that have been prepared and stored with and without proper preservation the use of method blanks and standard samples to determine the presence of determinate error and to establish single-operator characteristics and the use of spiked samples and recoveries to identify the presence of determinate errors associated with collecting and analyzing samples. 

Table 3.3 Tabulated operating characteristics, single sampling plans, normal inspection level with n = 200 [6] ...

Screens almost always focus on detecting a single endpoint of effect (such as mutagenicity, lethality, neurotoxicity, or development toxicity), and have a particular set of operating characteristics in common. 

Discrimination can be summarized by various single statistics, such as the area under the receiver operating characteristic curve (or the equivalent C statistic), measures, or the d statistic, although all of these measures have limitations (Royston and Sauerbrei 2004 Altman and Royston 2007 Lewis 2007). 

The overall separation depends on the single stage separation factor, the number of separating elements, and design and operating characteristics of the cascade. Equations 5-8 are insufficient to determine all the variables. It is instructive to consider three types of cascades the minimum stage cascade, the minimum reflux cascade, and the ideal cascade. The material balance equations from the i + 1 th stage to the product of the cascade lead to... 

The operating characteristic for this case of crossflow with a single row of tubes (one side laterally mixed crossflow) according to (1.131), gives the value of 1 required in (1.142) ... 

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