Single bonds functional groups with

Substitution yields products with other single-bonded functional groups. With hydrohalic acids, many alcohols give haloalkanes ... 

Compounds With Single-Bonded Functional Groups... 

This chapter finishes the coverage of functional groups with C-O and C—S single bonds that was begun in Chapter 17. We ll focus primarily on ethers and take only a brief look at thiols and sulfides before going on to an extensive coverage of compounds with C=0 bonds in Chapters 19 through 23. 

Alcohols, alkyl halides, ethers, and amines all have functional groups with single bonds. These compounds have many interesting uses in daily life. As you learn how to identify and name these compounds, think about how the intermolecular forces between their molecules affect their properties and uses. 

The data from Table 8 and the spectra in Fig. 27 indicate that a wide variety of functional groups with single and double oxygen-carbon bonds are formed after mild ozonization at 335 K in aqueous medium. The agreement between the assignments of the absorptions in both samples in quite remarkeable and agrees... 

Functional groups with only single bonds undergo substitution or elimination. 

Functional groups with both single and double bonds undergo substitution. 

Functional Groups with Only Single Bonds... 

Functional Groups with Both Single and Double Bonds... 

It is most desirable that a given amino acid should form a single-derivative peak after treatment with a single derivatization agent. Unfortunately, that is not the case for many important determinations. Thus, for example, permethylation [481] and the formation of W-dimethylaminomethylene alkyl esters [482] appeared limited to only some amino acids. Persilylation of all amino acid functional groups with potent silyl donors [483] comes perhaps closest to definition of a universal reaction , but even here some problems are encountered (a) derivatization can be time-consuming (b) multiple derivatives are occasionally formed even under precautions (c) Si-N bonds are moisture-sensitive and (d) truly quantitative derivatization is difficult to achieve for all protein amino acids. 

Functional Groups with Carbon Singly Bonded to an Electronegative Atom... 

Functional groups with both double and single bonds—carboxylic acids, esters, and amides—generally take part in substitution reactions. 

---