Simple cross injector

FIGURE 15.7 Subsecond chiral separation of DNS-norleucine achieved using a simple cross-injector quartz microchip. The separation was performed in a 1.5-mm-long channel, using an electric field of 2012 V cm and 1% highly sulfated y-cyclodexlrin, 25 mM triethylammonium phosphate buffer, pH 2.5, as the separation buffer. (Reproduced from Piehl, et al. Electrophoresis 25, 3848, 2004.)... 

Crevillen, A. G., Barrigas, L, Blasco, A. J., Gonzalez, M. C., and Escarpa, A., Microchip-electrochemistry route for rapid screening of hydroquinone and arhntin from miscellaneous samples Investigation of the robustness of a simple cross-injector system. Anal. ChirtL Acta, 562,137, 2006. 

Various injector geometries (simple cross, double-T, triple-T) were investigated on a glass microchip. The triple-T injector allowed for a selection of different injection volumes. For instance, a triple-T injector allowed injection of three different volumes depending on whether a cross, double-T, or triple-T configuration was used (see Figure 4.6) [529]. Pinched injection has been used consecutively to inject two samples into the same separation channel (see Figure 4.7) [557]. 

Figure 12.1 Common microchip layouts, (a) Simple cross-T injector and (b) Twin-T injector...

The typical layout of a microchip electrophoresis (both a simple cross T-injector (A), and a twin-T injector (B)) has been already depicted in Fig. 21.5. It has a network of channels with widths varying from 10 to 100 pm with typical straight separation channels between 3 and 10 cm. In a typical set-up, buffer solutions are introduced on sample (S), running buffer (RB), and waste (W) reservoirs. The... 

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