Simazine probabilistic risk assessment

Probabilistic Risk Assessment Using Atrazine and Simazine as a Model... 

Results of a probabilistic risk assessment indicate that neither occupational exposure nor environmental exposure to atrazine and simazine is likely to produce adverse health consequences in the US population. This conclusion is based on a quantitative risk assessment that potential human exposure to atrazine and simazine is much smaller than the intakes required to produce adverse health effects in animal experiments. 

This chapter presents a quantitative probabilistic risk assessment for atrazine and simazine conducted for Syngenta Crop Protection, Inc. The risk of an effect is the likelihood that an individual will develop the effect as a result of that individual s exposure to atrazine and/or simazine. The risk assessment is quantitative because it characterizes the likelihood in numerical terms. The risk assessment does include some qualitative discussion of the uncertainties associated with the quantitative characterization of the likelihood. It also assumes relevance of an animal effect in humans even when a lack of human relevance has been established, as is the case with atrazine and simazine [US Environmental Protection Agency (USEPA), 2006]. 

Sielken Jr., R.L., R.S. Bretzlaff, and C. Valdez-Flores (1998). Probabilistic risk assessment for atrazine and simazine. In L.G. Ballantine, J.E. McFarland, and D.S. Hackett, eds., Triazine Herbicides Risk Assessment. Washington, DC American Chemical Society, pp. 448456. 

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