Silver/ions with biomolecules

The dissolution rate and stability ofNMs over time is another crucial issue. Kittler et al. [32] have shown that the release of silver ions from a dispersion of silver nanoparticles in water, and consequently the toxicity towards human mesenchymal stem cells, increases significantly with time. In addition, the temperature and the nature of the biological medium (e.g., the presence of salts or biomolecules) are important factors influencing the dissolution of metal nanomaterials. Unfortunately, measurement of the dissolution... 

The UV-vis spectrometry has been used to observe the shape and size of the nano-particles in aqueous suspensions. For SNPs, the absorption spectrum was produced at different time intervals, which reveals nanoparticles produced within 1 h of the silver ions when it contacts biomolecules. The changes of color were observed from colorless to brown just after the addition of the plant extract to the solution of silver nitrate within 1 h. The sharp absorbance of SNPs was observed between 400 and 500 nm, with increasing reaction time by UV-vis spectrum (Mittal et al., 2013). Similarly, the changes of color were observed on GNPs after reduction of gold ions to GNPs on contact with the plant extract. The SPR band at about 500—600 nm after 2 min of reactions was observed at different time intervals for the reaction with aqueous chloroauric acid solution in UV-vis spectra (MubarakAli et al., 2011). 

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