Silkworm larva, inhibiting

Is easily observed as a gross morphological event In which the "old" cuticle remains enveloping the Insect In the pharate condition. The abnormal pharate condition prevents feeding and locomotion, and eventually results In the death of the affected Insect. The Inhibited ecdysls of a Bombyx morl (silkworm) larva Is shown In Figure 2. The larva underwent normal apolysls, but failed to complete ecdysls and could not remove Its head capsule or trunk exuvla and eventually died. 

Isoechinulins A, B, and C (22-24) have been isolated from the mycelium of Asp. ruber by Tamura and co-workers (37,48,53), in the course of screening for insecticidal metabolites of fungi. Among them, isoechinulin A causes growth inhibition of silkworm larvae (Bombyx mori L.) by oral administration at a concentration of 1000 ppm. 

Figure 2. Ecdysis Inhibition of a larva of the silkworm, Bombyx mori. The Insect underwent normal apolysis, but failed to complete ecdysis and could not remove its head capsule or trunk exuviae. Magnification X 12.

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