Silk Scaffolds for Tissue Engineering Applications

The ability to pattern 3D biocompatible scaffolds may lead to new fundamental understanding of tissue development and remodeling as well as the formation of multi-cellular aggregates in complex micro-environments that better mimic the targeted tissues of interest. Using direct-write assembly, 3D silk scaffolds for tissue 

By comparison with other methods for preparing 3D tissue engineering scaffolds from degradable polymeric systems, our approach confers important benefits such as finer fiber diameter, avoidance ofharsh processing conditions of temperature or toxic organic solvents, and the ability to precisely control complex architectures. Direct-write assembly offers a unique path forward in support ofbiomaterial scaffolding for 

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