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Silica based nanoparticles surface functionalization

Based on well established silica chemistry, the surface of silica nanomaterials can be modified to introduce a variety of functionalizations [3, 11, 118]. The toxicity of surface-modified nanomaterials is largely determined by their surface functional groups. As an example, Kreuter reported that an apolipoprotein coating on silica nanoparticles aided their endocytosis in brain capillaries through the LDL-receptor [122-124]. Overall, silica nanomaterials are low-toxicity materials, although their toxicity can be altered by surface modifications. [Pg.247]

Tuning the surface functionality of silica nanoparticles through a click chemistry-based protocol... [Pg.17]


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2 2 nanoparticle-based

Base function

Base surface

Function surface

Function-based

Nanoparticle Surface Functionalization

Silica based

Silica based nanoparticles

Silica surfaces

Silica, functionalization

Surface functionality

Surfacing function

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