Side-effect monitoring

Drug Type and Agent Starting Dose Maximal Dose Side Effects Monitoring Suggestions Preferred Indication... 

TACROUMUS GANCICLOVIR/ VALGANCICLOVIR Possible t nephrotoxicity/ neurotoxicity Additive side-effects Monitor more closely check tacrolimus levels... 

AMINOGLYCOSIDES FOSCARNET SODIUM Possible T nephrotoxicity Additive side-effect Monitor renal function closely... 

ETHAMBUTOL ANTIVIRALS-DIDANOSINE Possibly t adverse effects (e.g. peripheral neuropathy) with didanosine Additive side-effects Monitor closely for development of peripheral neuropathy but no dose adjustment is required... 

NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS ISONIAZID t adverse effects with didanosine and possibly stavudine Additive side-effects Monitor closely for the development of peripheral neuropathy, but no dose adjustment required... 

LAMIVUDINE ZIDOVUDINE Possibly t adverse effects Additive side-effects Monitor closely, especially for blood dyscrasias. Check FBC prior to concomitant use and then eveiy month for 3 months... 

Systemic steroids are also the cause of numerous negligence claims.These drugs have side effects that can result in serious injury, even death, and consequently must be used conservatively. Systemically administered drugs, with their risk of systemic complications, should not be used if a topical route of administration suffices, and practitioners must be prepared to justify the selection of a systemic route of administration when complications result and a topical route of administration initially was not used. Whenever systemic steroids are prescribed, practitioners must warn patients of side effects, monitor patients adequately so that preventable injuries can be detected, and document the care rendered. 

Women often seek relief for premenstrual and perimenopausal symptoms from alternative or nontraditional treatments without consulting their health care providers. Herbal therapies, phytoestrogens, progesterone creams, megavitamins, folk remedies, and homeopathy are marketed to women without scientific evidence of efficacy or safety. Clinicians should ask women if they use alternative/ complementary therapies and become familiar with the products (e.g., mechanism of action, efficacy, dosing, side effects, monitoring, and drug-herb and herb-herb interactions). 

Lithium tried and tested significant side effects, monitoring and toxicity risks... 

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