Sickle-Cell Anemia Society

Mr Robert Heflin again came to our rescue to link me up with funds to study in Cambridge via Ms. Ruth White, the then director of the Sickle-Cell Anemia Society in Pittsburgh. In one day, Ms. White arranged for me to get a Heinz Foundation grant to travel and work in Perutz s laboratory. 

Serves as president of the American Chemical Society publishes, with Harvey Itano and John Singer, an influential paper on the molecular basis of sickle-cell anemia... 

Figure 6.5 Identification of the sickle cell anemia gene mutation using two different DNA duplexes with inserted cytosine loops working as synthetic scaffolds to generate fluorescent silver clusters. Reproduced with permission from W. Guo, J. Yuan, Q. Dong and E. Wang,/. Am. Chem. Soc., 2010,132, 932. Copyright (2010) American Chemical Society. ...

The cost to society of sickle cell disease is high in terms of human suffering and in the financial burden of providing treatment to alleviate the pain and symptoms of the afflicted individnals and the loss of income to the individnals and their families and communities. Health problems due to sickle cell disease include chronic anemia, vaso-occlnsive crises, splenic sequestration, acute chest syndrome, stroke, splenic and renal dysfunction, and snsceptibility to bacterial infections (2,5,12). In Africa, treatments for sickle cell disease are limited... 

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