Short-range distances

Haes, A.J. Zou, S. Schatz, G..C. Van Duyne, R.P. (2004) Nanoscale optical biosensor Short range distance dependence of the localized surface plasmon resonance of noble metal nanoparticles. Journal of Physical Chemistry B 108 6961-6968. 

Figure 5.25 Diagrammatic illustration of the two main short range distances over which NOE distances may be seen in an organised polypeptide chain (a). Short range NOEs involving NW and C W protons are classically indicative of secondary structures as illustrated by the different patterns of short range NOEs that are developed by various different secondary structure elements (b). NOEs are classified as strong, medium or weak as reflected by the thickness of each band shown.

Figure 5.29 Diagrammatic illustration of the main short range distances over which NOE distances may be used to determine structure by NMR in an organised oligodeoxynucleob de (or oligonucleotide) single chain or duplex. Note that there are three main types of d////g (i-l, i) (purine) (a) or d////g (i-1, i) (pyrimidine) (b) distances and two main types of (inns (0 (purine) (a) or Ahh6 (0 (pyrimidine) (b) distances.

The NOESY experiments that yield 2D spectra show correlahon for pairs of protons that are in close proximity of each other, mostly for protons that are less than hve amino acid apart (short range) in the peptide sequence. Short-range distances (<2.5 A) invariably yield substantial NOEs, medium-range distances (2.5-3.5 A) yield weaker NOEs, while... 

A local structure similar to ideal orthorhombic- and monoclinic-like structures shown in Fig. 15A and Fig. 15B,B is retained at short-range distances, up to few tens of angstroms (2-3 times the lattice parameters). In other terms, on a local scale, the chains are arranged according to the orthorhombic-, monoclinic- or triclinic-like models of Fig. 15. 

A. J. Haes and R. P. Van Di e, A nanoscale optical biosensor The short range distance dependence of the... 

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