Serotonin with norepinephrine release, alpha

Another type of presynaptic norepinephrine receptor on serotonin neurons is the alpha 1 receptor, located on the cell bodies (Figs. 5—45 and 5—46). When norepinephrine interacts with this receptor, it enhances serotonin release. Thus, norepinephrine can act as both an accelerator and a brake for serotonin release (Table 5-22 and Figs. 5-47 and 5-48). 

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