Sequence-to-structure rules

The review is laid out as follows in Part II, there is a discussion of the structural features of the coiled-coil assemblies and the current state-of-the-art of sequence-to-structure rules pertinent to design in Part III, there is a detailed description of some of the key coiled-coil designs, including the rules used to create them and their significance in the field and, finally, there is a discussion of the potential for new coiled-coil designs and where the field might go in the future. 

---