Separation of Initial and Transition State Solvent Effects

Separation of Initial and Transition State Solvent Effects 

We have defined the solvent effect (medium effect) on a reaction by 8mAC = 8G - hGl = 

Here is one way to attack the problem. °- ° Equations (8-54) constitute definitions of AG in the two solvents  

As usual the double dagger signifies the transition state and R the reactant or initial state. Subtracting these equations, with slight rearrangement of terms, gives 

The quantity 8mG b is called the transfer free energy, it is the (standard) free energy 

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