Separation monosodium glutamate

Precipitation of monosodium glutamate Separation of precipitates (centrifugation)... 

The production of a-amino acids by chemical synthesis yields a mixture of DL forms. The D-fomi of glutamic acid has no flavor-enhancing properties and thus requires transformation into the optically active form insofar as monosodium glutamate is concerned. The three methods for separating the optical isomers are (1) preferential inoculation method ... 

OW Lau, CS Mok. Indirect conductometric detection of amino acids after liquid chromatographic separation. Part II. Determination of monosodium glutamate in foods. Anal Chim Acta 302 45 -52, 1995. 

While both aroma and taste are obviously important in developing a food product which will supply full mouth satisfaction, inadequate attention has been given to the importance of a proper balance of sweet, salty, sour, and bitter. This subject comes within the field of seasoning. More emphasis should be placed on studies of the role of the four primary taste factors in the seasoning of foods. Commercial practice puts the principal responsibility on salt and it is well known that monosodium glutamate plays a separate and important role in seasoning. 

The chiral pool refers to readily available optically active natural products, some of which are commercially used in quantities of 10 -10 tonnes per year [5], Among them, the most inexpensive compounds are a-amino acids, like monosodium L-glutamate, or carbohydrates, like dextrose or sorbitol. The success of the second method depends on the availability of particular catalysts. One rather special example, how efficient stereoselective synthesis can work, is the syn-selective aldol reaction followed by a stereoselective alkene hydroboration and ketone reduction (Figure 1.8) which were used by Paterson et aJ. [26] to synthesize intermediates for the antibiotic oleandomycin. According to Paterson et al., four new stereocenters are formed in only two synthetic steps [9]. For the purpose of separating racemic mixtures... 

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