Sensing analyte-recognition

In the same way, the host of a host-guest complex can fimction as, or as part of, a sensor. Sensors are devices that announce the presence of analytes via reversible, real-time signals discernible by one of the human senses. Molecular recognition complexes utilized toward this end fimction as reusable indicators. One school of thought holds that a sensor is a macroscopic device with wires and the like a pH meter is one such embodiment. We prefer the view that molecules themselves can be sensing devices as well. A solution of a colorimetric pH indicator fulfills all the requirements of a sensor the solution announces the presence of protons via a reversible, real-time signal discernible by one of the human senses (sight). 

Figure 28 Preparation of the photonic structural sensors from colloidal crystalline arrays (CCAs) is performed by in situ copolymerization of the polymerizable receptor to yield polymerized colloidal crystalline arrays (PCCAs). A receptor-analyte recognition process can affect the changes in the CCA periodicity, and, following Bragg s law, the wavelengths of diffracted and transmitted light, which serve as a signal for the sensing event.

MEMS Biosensors Based on Nanoparticles Nanoparticles are often utilized as an analyte recognition element in MEMS biosensors. Nanoparticles have a quite large sensing area mainly due to their extremely small size. This enhances the reaction possibility of biomolecules. Furthermore, sensitivity of the biosensor can be increased when metal nanoparticles are positioned between two metal electrodes. When the analyte conjugated with metal nanoparticle is captured between two electrodes, the electric field intensity is amplified. Gold, silver, metal oxide and magnetic nanoparticles are widely used for detection... 

Biosensors play a significant role in the monitoring of a wide range of diseases and pathogens. A biosensor is an analytical device, which incorporates a biological recognition element or bioreceptor which is capable of sensing the presence. 

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