Rearrangements semi pinacol

The lactone A was also used as starting material in the synthesis of the primary prostaglandins via an allylic substitution-semi-pinacolic rearrangement sequence (Ref. 2). 

The benzo[ >]furan-based core structure of galanthamine was constructed by a novel synthetic methodology making use of a NBS-initiated semi-pinacol rearrangement, leading to the desired products in high yields <06OL1823>. 

Bickley, J. E., Hauer, B., Pena, P. C. A., Roberts, S. M., Skidmore, J. The semi-pinacol rearrangement of homochiral epoxy alcohols catalyzed by rare earth triflates. J. Chem. Soc., Perkin Trans. 1 2001,1253-1255. 

Semi-pinacolic rearrangement of the B-norbromohydrin (527) afforded the novel linear structure (528) somewhat similar compounds are accessible from suitable 8,9-seco-diketones. ... 

In contrast, similar systems underwent semi-pinacol rearrangement promoted by rare earth triflates. Thus, treatment of epoxyalcohol 78 with 20 mol% of ytterbium triflate in methylene chloride cleanly produced the hydroxyketone 79 in 99% yield after three hours. Attempts to... 

Recent advances in the semi-pinacol rearrangement of a-hydroxy epoxides and related compounds 07CSR1823. 

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