Self-assembly Systems SAS

Most of the SAS have been reported in amphiphilic polymers, which show the ability to self-assemble due to the desolvation, collapse, and intermolecular association of the hydrophobic portions of monomers. In the case of charged (anionic, cationic, or zwitterionic) amphiphiles, further stability and structural specificity can be designed using intermolecular polar interactions, such as electrostatic and hydrogen bonding. Various biologically inspired materials 

Water-insoluble biodegradable polymers have also been injected in solutions with water-miscible, physiologically compatible solvents to show self-assembly via phase segregation. Following injection, the solvent diffuses into the tissue space and water diffuses to the polymer matrix. This results in the precipitation of water-insoluble polymer into a matrix at the injection site. The solvent systems that have been reported based on this approach are propylene glycol, acetone, 2-pyrrolidone, tetrahydrofuran, Wmethyl-2-pyrrolidone, and dimethyl sulfoxide. The rate of precipitation of the polymer depends upon many factors such as the concentration of the polymer in solvent, the molecular weight of the polymer, the solvent used, and the addition of a surfactant.  

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