Self-assembly extended-site binding model

The thermodynamics of self-assembled systems are often characterized by positive co-operativity at the molecular level, however the thermodynamic analysis of co-operativity in self-assembly is complexes such as helicates is complicated by the occurrence of both inter- and intramolecular steps. It may be understood using the extended site binding model. 

The group of Piguet has extensively apphed the extended site binding model to rationalize the self-assembly behaviour of a large number of polymetallic complexes, especially of the f-block. The many interesting results obtained by Piguet and coworkers are outside the scope of the... 

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