Selectivity coefficients interfacial potential

The interfacial pd selectivity coefficient, the factor multiplying a is determined by the ratio K /K, by the activity coefficient ratio, and by the mobility ratio, when the internal diffusion potential contribution is added. Clearly interferences should correlate with the ratio K /1C, which can be determined from salt extraction coefficients K KX/K K for a series of positive drugs, using common anion salts. This result is well documented in the literature (7,8). A curious correlation for N-based drugs studied by us and by Freiser ( ) is a trend in selectivity... 

As stated before, an addition of compatibilizer requires miscibility of one part of copolymer in ole polymeric phase, and miscibility of the second part in another. When the dissolved copolymer parts have molecular weight above the entanglement molecular weight value, the polymeric compatibilizer offers not only the interfacial activity, but also a mechanism for enhanced adhesion and stress transfer in the solid state. By contrast, the low molecular weight additives are forced by the laws of thermodynamics to diffuse into the interfacial space between the two principal polymeric phases. When properly selected, it also diffusses into the two phases, bringing their chemical potential closer, i.e., reducing the interfacial tension coefficient. 

---