Seizures cavernoma

Another reason for patient s referral to a MRI unit is seizures (Gumus et al. 2007). There might be an association between DVA and epilepsy, even if the EEG focus is not congruent with the location of the DVA. If this is true, one should take a careful look for an associated cavernoma, cavernomas being known to cause different types of epilepsy, mainly due to their content of hemosiderin. 

As mentioned above, the majority of patients with cavernomas present with seizures as initial symptom (Moran et al. 1999). It is important to know that in the vast majority of patients these seizures are not related to acute bleeding events, but to hemosiderin deposition adjacent to neurons. Hemosiderin or ferritin is a well-known epileptogenic agent (at least in animal experiments). Being aware of the relation between seizures and hemosiderin deposition is of particular importance if surgical removal of the cavernoma is considered due to conservative untreatable seizures. It is of utmost importance not only to remove those parts of the cavernoma with... 

Zentralbl Neurochir 67 110-116 Ferroli P, Casazza M, Marras C, Mendola C, Franzini A, Broggi G (2006) Cerebral cavernomas and seizures a retrospective study on 163 patients who underwent pure le-sionectomy. Neurol Sci 26(6) 390-394 Ferszt R (1989) Kreislaufstorungen des Nervensystems. In Cervos-Navarro J, Ferszt R (eds) Klinische Neuropatholo-gie. Thieme, Stuttgart, p 112... 

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