Segmental rearrangement

This is the damage to chromosomes, resulting in large scale aberrations, including strand breaks and displacements, terminal and interstitial deletions of segments, rearrangements, and exchange between chromosomes. 

Receptor genes Fixed in genome Complement proteins Encoded in gene segments rearrangement necessary... 

Hoogenboom, H. R and Winter, G. (1992) By-passing immunization, human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro J Mol Biol 227, 381—388. 

Hoogenboom HR, Winter G, Bypassing immunisation human antibodies from synthetic repertoires of germ line VH-gene segments rearranged in vitro, J. Mol. Biol., 227 381-388, 1992. 

This equation results from the model characterised by Eqs. (2.84) - (2.88). Under dynamic conditions T < T , and protein molecules increase their number of adsorbed segments each occupying an area C0, while when > r. earlier adsorbed segments rearrange to leave the interface. The transfer between the different states may be described by a first order reaction... 

These quite different behaviors of energy release shown in the DSC experiments provide a direct demonstration that while the molecular-orientation-induced free-energy storage occurs incrementally in the intense and chaotic segmental rearrangements occurring in the STs as they form, it is a separate and largely... 

Reactions that are bimolecular can be affected by the viscosity of the medium. The translational motions of flexible polymeric chains are accompanied by concomitant segmental rearrangements. Whether this applies to a particular reaction, however, is hard to tell. For instance, two dynamic processes affect reactions, like termination rates, in chain-growth polymerizations. If the termination processes are controlled by translational motion, the rates of the reactions might be expected to vary with the translational diffusion coefhcients of the polymers. Termination reactions, however, are not controlled by diffusions of entire molecules, but only by segmental diffusions within the coiled... 

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