Seed germination inhibitor

Triumferol or 4-hydroxyisoxazole (9) is the powerful seed germination inhibitor isolated from the African medicinal plant Triumfetta rhomboidea. Confirmation of its structure and its activity was obtained by synthesis through conversion of ethyl isoxazole-3-carboxylate into its acid chloride followed by reaction with MeMgBr... 

Bradow, j. M. and W. J. Connick, Jr., Volatile seed germination inhibitors from plant residues, J. Chem. Ecol., 16, 645-666 (1990). 

A series of phenylpropanoid compounds fromPimpinella spp. (Apiaceae) that contained epoxide rings were powerful seed germination inhibitors (Cutler, 1992). 

Stewart JW, Naylor AW (1953) Isolation of a seed germination inhibitor from tomato juice. Proceedings of the American Society of Plant Physiologists. University of Florida, Gainesville, FL., September 1953, p 23... 

Nakatani M, Yamachika T, Tanoue T, Hase T 1985 Structures and synthesis of seed-germination inhibitors from Hibiscus rosa-sinensis. Phytochemistry 24 39-42... 

There are several naturally occurring isoxazoles with interesting biological activity. Eor example. Muscimol and 4-hydroxy isoxazole, are seed-germination inhibitors... 

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