Secondary Substances Formed from L-Isoleucine

L-Isoleucine, 2(S),3(S)-2-amino-3-methylpentanoic acid, is an amino acid with a branched carbon chain comprising 6 C-atoms. Most secondary products derived from L-isoleucine still possess this characteristic carbon skeleton. 

Secondary products formed from L-isoleucine were found in plants and animals. Biosynthesis of j Isoleucine 

L-Isoleucine originates from 2-oxobutyric acid, a threonine derivative and activated acetaldehyde (C 4) as outlined in Fig. 196. Both compounds condense to form tx-aceto-a-hydroxybutyric acid from which 2,3-dihydroxy-3-methyl- 

Synthesis of the aspartate family and branched-chain amino acids. In The Biochemistry of Plants, Vol. 5, Amino Acids and Derivatives (B. J. Miflin, ed.), pp. 403-452. Academic Press, New York 1980 

Alkaloids derived from histidine and other precursors. In Encyclopedia of Plant Physiology, New Series, Vol. 8, Secondary Plant Products (E. A. Bell, B. V. Charlwood, eds.), pp. 160-166. Springer, Berlin-Heidelberg-New York 1980 

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