Secondary gain, lack

The flow of heat across the heat-transfer surface is linear with both temperatures, leaving the primary loop with a constant gain. Using the coolant exit temperature as the secondary controlled variable as shown in Fig. 8-55 places the jacket ( mamics in the secondary loop, thereby reducing the period of the primary loop. This is dynamically advanti reous for a stirred-tank reactor because of the slow response of its large heat capacity. However, a plug flow reactor cooled by an external heat exchanger lacks this heat capacity and requires the faster response of the coolant inlet temperature loop. 

The structural information gained from the analysis of myoglobin served as the basis for hypotheses on tertiary structure. However, myoglobin is an atypical globular protein since it lacks cysteinyl residues (no disulphide bonds) and P-con-formation, but contains a very large proportion of a-helical structure. Studies on over 200 globular proteins have demonstrated that polypeptide chains frequently contain both a-helical and P-sheet secondary structures (Figure 4.16). 

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