Searching of Multiple Three-Dimensional Pharmacophoric Patterns

Databases and Searching of Multiple Three-Dimensional Pharmacophoric Patterns 

The work above shows that it is possible to describe the three-dimensional and substructural requirements for a molecule to have a particular biological activity. This suggests that such descriptions could be used in a computer program that would evaluate proposed compounds in each of the known pharmacophoric descriptions to alert the scientist to possible side-effects or additional therapeutic potential of a compound. 

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