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Scopolamine solid phase extraction

The application of MIPs as the stationary phase in solid-phase extraction (SPE), often referred to as molecularly imprinted polymer solid-phase extraction (MIS P E), is a rapidly growing area [197-199]. With MISPE, highly specific enrichment of substances present at trace levels is possible. The technique has been applied to the analysis of drugs, for example, caffeine [200], scopolamine [201], naproxen [202], tetracycline [203], cholesterol [204] and local anesthetics [205], as well as environmental pollutants, exemplified by organophosphate flame retardants [206-208], triazines in soil and vegetable samples [71] and naphthalene sulfonates in river water [209]. [Pg.35]

Whelpton, R. Hurst, P.R. Metcalfe, R.F. Saunders, S.A. Liquid chromatographic determination of hy-oscine (scopolamine) in urine using solid phase extraction. Biomed.Chromatogr, 1992, 6, 198-204 Achari, R.G. Jacob, J.T. A study of the retention behavior of some basic drug substances by ion-pair HPLC. J.Liq.Chromatogr., 1980, 3, 81-92 [also N-acetylprocainamide, antazoline, atropine, caffeine, chlorpheniramine, codeine, ephedrine, epinephrine, naphazoline, papaverine, pheniramine, phenylephrine, phenylpropanolamine, procainamide, quinidine, xylocaine]... [Pg.1243]

Figure 4 Elution patterns of hyoscine (scopolamine) and its dehydrated metabolite, apohyoscine, from Cis SPE columns. Hyoscine (A) or apohyoscine (B) eluted with 40% (v/v) methanoliwater and hyoscine (C) or apohyoscine (D) eluted with 50% (v/v) metha-noliwater. The latter eluent was chosen for the assay as >90% of hyoscine was recovered in the first milliliter, whereas <5% of the apohyoscine was eluted in this volume. Washing with 20% (v/v) methanol removed the majority of the urinary pigments but not the hyoscine. (Reproduced with permission from Whelpton R, Hurst PR, Metcalfe RF, and Saunders SA (1992) Liquid chromatographic determination of hyoscine (scopolamine) in urine using solid phase extraction Biomedical Chromatography 6. 198-204 John Wiley Sons Ltd.)... Figure 4 Elution patterns of hyoscine (scopolamine) and its dehydrated metabolite, apohyoscine, from Cis SPE columns. Hyoscine (A) or apohyoscine (B) eluted with 40% (v/v) methanoliwater and hyoscine (C) or apohyoscine (D) eluted with 50% (v/v) metha-noliwater. The latter eluent was chosen for the assay as >90% of hyoscine was recovered in the first milliliter, whereas <5% of the apohyoscine was eluted in this volume. Washing with 20% (v/v) methanol removed the majority of the urinary pigments but not the hyoscine. (Reproduced with permission from Whelpton R, Hurst PR, Metcalfe RF, and Saunders SA (1992) Liquid chromatographic determination of hyoscine (scopolamine) in urine using solid phase extraction Biomedical Chromatography 6. 198-204 John Wiley Sons Ltd.)...

See other pages where Scopolamine solid phase extraction is mentioned: [Pg.347]    [Pg.360]    [Pg.309]   
See also in sourсe #XX -- [ Pg.343 ]




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