Scale Irreversible Quaternary Structure Changes in Double-Stranded DNA Bacteriophage

Large-Scale Irreversible Quaternary Structure Changes in Double-Stranded DNA Bacteriophage 

Introduction to Tailed Double-Stranded DNA Phage and HK97 

A breakthrough in the study of HK97 was achieved when an Escherichia coli expression system was developed in which gene 4 and gene 5 products alone were shown to assemble and mature in a manner identical with the authentic virus (Xie and Hendrix, 1995). Expansion was triggered by 

Change in Subunit Interactions and Locations during Transition 

Buried Surface Area between Prohead and Head 

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