Scaffolds fabrication containing electrospun

Scientists have fabricated scaffolds in a two-step approach that combines an in situ coprecipitation synthesis route with the electrospinning process to prepare a novel type of biomimetic nanocomposite nanofibres of HA/CHT. The electrospun composite nanofibres of HA/CHT, with compositional and structural features close to the natural mineralised nanofibril counterparts, are of potential interest for bone TE. The results of HA/CHT indicate that although an initial inhibition occurs, the nanofibrous scaffolds which contained HA, as compared to scaffolds of CHT alone, appeared to have significantly stimulated the bone forming ability as shown by the cell proliferation, mineral deposition, and morphological observations, due to the excellent osteoconductivity of HA [19, 34, 56, 70]. 

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