Sansert

Methysergide (Sansert ) is believed to alter the ability of serotonin to cause inflammation, platelet aggregation (blood clotting), and dilation of blood vessels. However, methysergide has some undesirable side effects, such as motor incoordination and dizziness and can cause heart problems. Usually, the drug is intentionally discontinued for 4-6 weeks twice a year because of these problems. Thus, methysergide is used only in special cases. 

Synonym. 1-Methyl-D-lysergic Acid Butanolamide Maleate Proprietary Names. Deseril Desernil Sansert. 

SYNS l-(HYDROXYMETHYL)PROPYLAM]DEofl-METHYL-(+)-LYSERGIC ACID HYDROGEN MALEATE METHYLSERGIDE BIMALEATE SANSERT... 

Trade names Deseril Desernil Deserril Deseryl Sansert (Novartis)... 

Hydrogen maleate, CjjHjjNjOj, methysergide maleate, Deserif, Dfsemil-Sandoz, Sansert. 

Sandril (reserpine solution)—304 San Pedro cactus Trichocereuspachanoi)— 87,99-103,115,308,396,419,639 San Pedro de Atacama, Chile-168 Sansert (methysergide)-i2g,i49,445 Santal tribal people of India—258,345,347 Santa Marla Cannabis sp.)—267 Santesson, C.G.—125,127,151,298 Santo Zirrme—242-4,252,266-8 sassafras Sassafras albidum root bark)—90 Sathapatha Brahmana—yp > saumya Desmodium gangeticum)—z y, /pyj scammony Convolvulus scammonia)— yL Schenk, G. (psychonautic pioncer)-369... 

B. Specific drugs and antidotes. For suspected serotonin syndrome, anecdotal reports claim benefit from cyproheptadine (Periactin), 4 mg orally every hour for 3 doses, or methysergide (Sansert), 2 mg orally every 6 hours for 3 doses, presumably because of the serotonin antagonist effects of these drugs. 

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