Salvia desoleana

Fatty acid esters would be predicted to have little irritation or toxic effects. Ex vivo permeability studies conducted in porcine buccal mucosa showed significant permeation enhancement of an enkephalin from liquid crystalline phases of glycerine monooleate [32]. These were reported to enhance peptide absorption by a cotransport mechanism. Diethylene glycol monoethyl ether was reported to enhance the permeation of essential oil components of Salvia desoleana through porcine buccal mucosa from a topical microemulsion gel formulation [33]. Some sucrose fatty acid esters, namely, sucrose laurate, sucrose oleate, sucrose palmitate, and sucrose stearate, were investigated on the permeation of lidocaine hydrochloride [34], with 1.5% w/v sucrose laurate showing a 22-fold increase in the enhancement ratio. 

Ceschel, G.C., et al. 2000. In vitro permeation through porcine buccal mucosa of Salvia desoleana Atzei Picci essential oil from topical formulations. Int J Pharm 195 171. 

Roda A, Aldini R, Grigolo B et al. (1988) 23-Methyl-3a,7b-dihydroxy-5b-cholan-24-oic acid Dose-response study of biliary secretion in rat. Hepatol 8 1571-1576 Paglietti G, Sanna P, Carta A et al. (1994) Choleretic activity of 3-[ring substituted benzotriazol-l(2)yl]alkanoic and alkenoic adds. Farmaco 49 693-702 Peana A, Satta M, Luigi-Moretti MD, Orecchioni M (1994) A study on choleretic activity of Salvia desoleana essential oil. Planta Med 60 478 179... 

PHARMACOLOGICAL ACTIVITIES AND APPLICATIONS OF SALVIA SCLAREA AND SALVIA DESOLEANA ESSENTIAL OILS... 

SALVIA DESOLEANA ATZEI TPICCI General and Botanical description... 

Peana A., Moretti M., and C. Julidano, 1999. Chemical composition and antimicrobial action of the essential oils of Salvia desoleana and S. sclarea. Planta Med., 65 751-754. 

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